At least two migrants have died and 14 others are in critical condition after they were found in a train car near a small Texas town in Uvalde County, the Texas Department of Public Safety said.
The incident is suspected to be related to human smuggling, sources said.
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Uvalde Mayor Don McLaughlin told Fox News that six life flights had already flown out with more medical resources on the way.
The incident comes less than a year after 53 migrants died after being found inside a tractor trailer in the searing summer heat outside of nearby San Antonio.